Related: Celebrities Who’ve Spoken About the Ozempic Weight Loss Trend
Celebrity
Amy Schumer Praises Mounjaro After She ‘Couldn’t Handle’ Wegovy

Amy Schumer had some positive praise for Mounjaro after a not-so-great experience with Wegovy years prior.
“Three years ago, I tried Wegovy,” Schumer, 43, said in a video shared via Instagram on Friday, March 21. “I was puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever. But anyway, I went on this Telehealth meeting with Midi Health, and it was cheap. I wanted to try it myself ‘cause I wanted to recommend it to my friends who are nurses and teachers.”
Midi Health, per the official website, is a virtual care clinic specializing in the treatment of menopause and perimenopause.
“They put me on estrogen and progesterone because I realized I was in perimenopause and my symptoms from being perimenopause have disappeared,” Schumer said. “My hair is fuller, my skin is better, I have more energy, I want to get down more, if you know what I mean. I’m talking about sex. So that’s been great and Mounjaro’s been great.”
According to WebMD, while Mounjaro is similar to other drugs such as Wegovy or Ozempic in that they all contain GLP-1 that assist in weight loss, Mounjaro is specifically designed to help diabetes patients with weight management. Common side effects of these drugs can include nausea and diarrhea.
“And, look, it’s not covered by insurance unless you have diabetes or like severe obesity, which most of the internet thinks I have,” Schumer said of Mounjaro. “But I’m having a really good experience with it and I wanted to keep it real with you about that.”
She concluded, “Midi Health. I liked it so much and I had such a good experience [that] I invested in the company.”
Like Schumer, the drug has also been used by other celebrities such as Scott Disick, Whoopi Goldberg and Jim Gaffigan. “I was so paranoid that I was going to be nauseous that I kind of put it off, but then it kind of worked,” Gaffigan, 58, exclusively told Us Weekly in November 2024.
In June 2023, Schumer had opened up about her experience using Ozempic, saying during an appearance on Watch What Happens Live With Andy Cohen, “I was one of those people that felt so sick and couldn’t play with my son. I was so skinny and he’s throwing a ball at me and [I couldn’t].”
At the time, Schumer noted that while she decided using the drug wasn’t “liveable for [her],” she still “immediately invested because I knew everyone was going to try it.”
